Mustered into service as a Private on July 29th, 1861
Died 13 August 1864
Buried Beech Grove Cemetery, Delaware County Indiana
Private Hughes was wounded at the Battle of Gettysburg on July 1st, 1863 that resulted in the loss of his right arm. He was discharged from the service later that year for disability.
He filed for a pension in December of 1863.
Isaac was murdered a year later in Muncie Indiana.